1-[(2-BroMoethyl)sulfonyl]-4-Methylbenzene
4-[(5Z)-5-(3-fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid
CAS: 5755-76-0
Molecular Formula: C9H11BrO2S
1-[(2-BroMoethyl)sulfonyl]-4-Methylbenzene - Names and Identifiers
| Name | 4-[(5Z)-5-(3-fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid |
| Synonyms | 1-[(2-BroMoethyl)sulfonyl]-4-Methylbenzene 1-[(2-Bromoethyl)sulfonyl]-4-methylbenzene 4-[(5Z)-5-(3-fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid 3-Thiazolidinebutanoic acid, 5-[(3-fluorophenyl)methylene]-4-oxo-2-thioxo-, (5Z)- |
| CAS | 5755-76-0 |
| InChI | InChI=1/C14H12FNO3S2/c15-10-4-1-3-9(7-10)8-11-13(19)16(14(20)21-11)6-2-5-12(17)18/h1,3-4,7-8H,2,5-6H2,(H,17,18)/b11-8- |
1-[(2-BroMoethyl)sulfonyl]-4-Methylbenzene - Physico-chemical Properties
| Molecular Formula | C9H11BrO2S |
| Molar Mass | 263.15 |
| Density | 1.49g/cm3 |
| Boling Point | 509.6°C at 760 mmHg |
| Flash Point | 262°C |
| Vapor Presure | 3.29E-11mmHg at 25°C |
| Refractive Index | 1.681 |
1-[(2-BroMoethyl)sulfonyl]-4-Methylbenzene - Introduction
4-[(5Z)-5-(3-fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid, the chemical structure of which is 4-[(5Z)-5-(3-fluorobenzimido) -4-oxo-2-thio-1, 3-thiazolidin-3-yl]butanoic acid. The compound has the following properties:
Nature:
-Appearance: Colorless or light yellow solid
-Molecular weight: 426.47g/mol
-Melting point: about 140 degrees Celsius
-Solubility: Slightly soluble in water
Use:
4-[(5Z)-5-(3-fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid is a reagent commonly used in organic synthesis. It can be used in the synthesis of biologically active compounds, such as pharmaceutical and pesticide intermediates. Specific applications include anti-infective drugs, anti-tumor drugs and anti-inflammatory drugs.
Preparation Method:
4-[(5Z)-5-(3-fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid can be prepared by reacting 4-methylphenylsulfoethyl azide hydrochloride with boron pentafluoride or other electrophilic reagents. During the preparation process, attention should be paid to the operating environment and safety equipment to avoid harm to the human body and the environment.
Safety Information:
4-[(5Z)-5-(3-fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid should pay attention to the following safety matters during use:
-Avoid direct contact with skin and eyes, wear protective gloves and goggles if necessary.
-Operate in a well-ventilated place to avoid inhaling gas or dust. If inhaled, should quickly leave the scene, and timely medical treatment.
-When storing, keep it dry and away from fire and oxidant.
When using this compound, it is recommended to strictly follow relevant safety procedures and comply with relevant regulations.
Nature:
-Appearance: Colorless or light yellow solid
-Molecular weight: 426.47g/mol
-Melting point: about 140 degrees Celsius
-Solubility: Slightly soluble in water
Use:
4-[(5Z)-5-(3-fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid is a reagent commonly used in organic synthesis. It can be used in the synthesis of biologically active compounds, such as pharmaceutical and pesticide intermediates. Specific applications include anti-infective drugs, anti-tumor drugs and anti-inflammatory drugs.
Preparation Method:
4-[(5Z)-5-(3-fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid can be prepared by reacting 4-methylphenylsulfoethyl azide hydrochloride with boron pentafluoride or other electrophilic reagents. During the preparation process, attention should be paid to the operating environment and safety equipment to avoid harm to the human body and the environment.
Safety Information:
4-[(5Z)-5-(3-fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid should pay attention to the following safety matters during use:
-Avoid direct contact with skin and eyes, wear protective gloves and goggles if necessary.
-Operate in a well-ventilated place to avoid inhaling gas or dust. If inhaled, should quickly leave the scene, and timely medical treatment.
-When storing, keep it dry and away from fire and oxidant.
When using this compound, it is recommended to strictly follow relevant safety procedures and comply with relevant regulations.
Last Update：2024-04-09 19:05:50
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